Methanol → 5-(2-Fluoro-4-{[2-(tetrahydropyran-4-yl)ethylamino]methyl}phenoxy)pyrazine-2-carboxamide
Reaction equation
[BH4-:29].[CH3:31][OH:32].[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([C:11](=[O:12])[NH2:13])[n:9][cH:10]2)[cH:14][cH:15][c:16]([CH:18]=[O:19])[cH:17]1.[Na+:30].[O:20]1[CH2:21][CH2:22][CH:23]([CH2:26][CH2:27][NH2:28])[CH2:24][CH2:25]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([C:11](=[O:12])[NH2:13])[n:9][cH:10]2)[cH:14][cH:15][c:16]([CH2:18][NH:28][CH2:27][CH2:26][CH:23]2[CH2:22][CH2:21][O:20][CH2:25][CH2:24]2)[cH:17]1Participants
6
Sources & evidence
- ORD record
- ord-a212e6a0e00243b694be788fdd7d3af9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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