2-Amino-6-bromopyridine → [5-(4-Fluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine

Reaction equation

[CH3:1][c:2]1[n:3][s:4][c:5]([N:7]2[CH2:8][CH2:9][C:10](=[O:13])[CH2:11][CH2:12]2)[n:6]1.[F:14][c:15]1[cH:16][cH:17][c:18](-[c:21]2[cH:22][cH:23][cH:24][c:25]3[n:26]2[n:27][c:28]([NH2:30])[n:29]3)[cH:19][cH:20]1.[NH2:31][c:32]1[cH:33][cH:34][cH:35][c:36]([Br:37])[n:38]1>>[CH3:1][c:2]1[n:3][s:4][c:5]([N:7]2[CH2:8][CH2:9][CH:10]([NH:30][c:28]3[n:27][n:26]4[c:21](-[c:18]5[cH:17][cH:16][c:15]([F:14])[cH:20][cH:19]5)[cH:22][cH:23][cH:24][c:25]4[n:29]3)[CH2:11][CH2:12]2)[n:6]1