Ethanol → 2-amino-7-aminomethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester

HRID 88725

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([NH2:29])[s:10][c:11]2[c:16]1[CH2:15][CH2:14][O:13][CH:12]2[CH2:17][N:18]1[C:19](=[O:20])[c:21]2[c:22]([cH:23][cH:24][cH:25][cH:26]2)[C:27]1=[O:28].[CH3:33][CH2:34][OH:35].[NH2:31][NH2:32].[OH2:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9]([NH2:29])[s:10][c:11]2[c:16]1[CH2:15][CH2:14][O:13][CH:12]2[CH2:17][NH2:18]

Participants

Reactant 4

HCID 702Ethanol

HCID 962Water

HCID 9321Hydrazine

HCID 545053682-amino-7-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester

Product 1

HCID 695860292-amino-7-aminomethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester

Sources & evidence

ORD record: ord-20699bfc1d324c0399cc144caada8508
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Linked notes

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