Methyl iodide → 2-cyclopropyl-4-iodo-1-methyl-1H-imidazole

Reaction equation

[CH:1]1([C:4]2[NH:5][C:6]([I:9])=[CH:7][N:8]=2)[CH2:3][CH2:2]1.I[CH3:11]>>[CH:1]1([C:4]2[N:8]([CH3:11])[CH:7]=[C:6]([I:9])[N:5]=2)[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 219853922-cyclopropyl-5-iodo-1H-imidazole

Product 1

HCID 219853842-cyclopropyl-4-iodo-1-methyl-1H-imidazole

Procedure

The title compound, MS: m/e=249.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-cyclopropyl-5-iodo-1H-imidazole (example C) and iodomethane.

Sources & evidence

ORD record: ord-775a03628f4f4a1c86c6343eb6cf66fb
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07091222B2

Reaction notes

Loading…