2-Bromo-1,1-difluoroethane → 1H-Imidazole, 1-(2,2-difluoroethyl)-4-iodo-2-methyl-

HRID 8881

Reaction equation

HRID 8881 reaction equation
[I:1][C:2]1[NH:6][C:5]([CH3:7])=[N:4][CH:3]=1.Br[CH2:9][CH:10]([F:12])[F:11]>>[F:11][CH:10]([F:12])[CH2:9][N:4]1[CH:3]=[C:2]([I:1])[N:6]=[C:5]1[CH3:7]

Participants

3

Reactant 2

HCID 1361862-Bromo-1,1-difluoroethaneHCID 27946235-Iodo-2-methyl-1H-imidazole

Product 1

HCID 219853931H-Imidazole, 1-(2,2-difluoroethyl)-4-iodo-2-methyl-

Procedure

The title compound, MS: m/e=273.0 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-methyl-1H-imidazole and 2-bromo-1,1-difluoroethane.

Sources & evidence

ORD record
ord-1942be038c934a82986d828342141348
Source dataset
uspto-grants-2006_08
Patent number
US07091222B2

Linked notes

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