HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine → 2-Chloro-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine | HCID 21985391 | — |
| Reactant | 4-Iodo-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazole | HCID 21985398 | — |
| Product | 2-Chloro-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridine | HCID 11472091 | — |
Reaction Steps
The title compound, MS: m/e=300.0 (M+H+), was prepared in accordance with the general method of example A, step 2, from 2-chloro-4-trimethylsilanylethynyl-pyridine and 4-iodo-2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091222B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-5c00e3d49dd94ec4bbdbd013597f9057 |
| Source note | uspto-grants-2006_08 |