Methanol → N-Me-D-Lys-OH.HCl

HRID 888753

Reaction equation

HRID 888753 reaction equation
Cl.[NH2:2][C@@H:3]([C:9]([OH:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8].S(Cl)([Cl:14])=O.[CH3:16]O>>[ClH:14].[CH3:16][NH:2][C@@H:3]([C:9]([OH:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8]

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 81691Lysine hydrochloride, D-

Product 1

HCID 86638777N-Me-D-Lys-OH.HCl

Procedure

In the first step, D-lysine monohydrochloride reacts with thionyl chloride in the presence of methanol to give methyl-D-lysinate hydrochloride.

Sources & evidence

ORD record
ord-545ffe30c9724b34b5f4e6b95be997cd
Source dataset
uspto-grants-2012_08
Patent number
US08252783B2

Linked notes

Loading…