4-Iodo-2-methylpyridine → 4-(1-Cyclopropyl-2,5-dimethyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

HRID 8888

Reaction equation

HRID 8888 reaction equation
[CH:1]1([N:4]2[C:8]([CH3:9])=[C:7]([C:10]#[CH:11])[N:6]=[C:5]2[CH3:12])[CH2:3][CH2:2]1.I[C:14]1[CH:19]=[CH:18][N:17]=[C:16]([CH3:20])[CH:15]=1>>[CH:1]1([N:4]2[C:8]([CH3:9])=[C:7]([C:10]#[C:11][C:14]3[CH:19]=[CH:18][N:17]=[C:16]([CH3:20])[CH:15]=3)[N:6]=[C:5]2[CH3:12])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 126913224-Iodo-2-methylpyridineHCID 219853851-cyclopropyl-4-ethynyl-2,5-dimethyl-1H-imidazole

Product 1

HCID 692908334-(1-Cyclopropyl-2,5-dimethyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

Procedure

The title compound, MS: m/e=252.1 (M+H+), was prepared in accordance with the general method of example A, step 1 from 1-cyclopropyl-4-ethynyl-2,5-dimethyl-1H-imidazole and 4-iodo-2-methyl-pyridine.

Sources & evidence

ORD record
ord-c57c50f18db24a3cb9c137f67aa88a92
Source dataset
uspto-grants-2006_08
Patent number
US07091222B2

Linked notes

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