(Pyrimidin-5-yl)boronic acid → 2-[3-(2-Methylpyrrolidin-1-yl)cyclobutyl]-6-quinolin-3-yl-1,3-benzothiazole

HRID 89028

Reaction equation

HRID 89028 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([CH:9]3[CH2:10][CH:11]([N:13]4[CH:14]([CH3:18])[CH2:15][CH2:16][CH2:17]4)[CH2:12]3)[s:8]2)[cH:19][cH:20]1.[CH3:21][C:22]1([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27][B:28]([c:29]2[cH:30][n:31][c:32]3[cH:33][cH:34][cH:35][cH:36][c:37]3[cH:38]2)[O:39]1.[n:40]1[cH:41][c:42]([B:43]([OH:44])[OH:45])[cH:46][n:47][cH:48]1>>[c:2]1(-[c:29]2[cH:30][n:31][c:32]3[cH:33][cH:34][cH:35][cH:36][c:37]3[cH:38]2)[cH:3][c:4]2[c:5]([n:6][c:7]([CH:9]3[CH2:10][CH:11]([N:13]4[CH:14]([CH3:18])[CH2:15][CH2:16][CH2:17]4)[CH2:12]3)[s:8]2)[cH:19][cH:20]1

Participants

4

Reactant 3

HCID 2795193(Pyrimidin-5-yl)boronic acidHCID 108485903-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolineHCID 692313126-Bromo-2-[3-(2-methylpyrrolidin-1-yl)cyclobutyl]-1,3-benzothiazole

Product 1

HCID 732317262-[3-(2-Methylpyrrolidin-1-yl)cyclobutyl]-6-quinolin-3-yl-1,3-benzothiazole

Sources & evidence

ORD record
ord-c6feca92d16047f6b555ca3c07d490c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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