Potassium Iodide → Methyl 2-acetyloctanoate

HRID 890700

Reaction equation

[CH3:1][O:2][C:3](=[O:8])/[CH:4]=[C:5](/[O-:7])\[CH3:6].[Na+].[I-].[K+].[CH2:12](Br)[CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>>[C:5]([CH:4]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:3]([O:2][CH3:1])=[O:8])(=[O:7])[CH3:6]

Participants

Reactant 3

HCID 4875Potassium Iodide

HCID 81011-Bromohexane

HCID 23681258sodium (2E)-4-methoxy4-oxo-2-buten-2-olate

Product 1

HCID 3390996Methyl 2-acetyloctanoate

Procedure

Analogously to Example 14A, 30 g (217 mmol) of sodium (2E)-4-methoxy-4-oxo-2-buten-2-olate (Example 13A) and 1.24 g (7.5 mmol) of potassium iodide are reacted with 37.7 g (228 mmol) of hexyl bromide to give methyl 2-acetyloctanoate.

Sources & evidence

ORD record: ord-595fc6a914d64e1fbf8e10003148cc40
Source dataset: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06998402B2

Linked notes

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