Ammonia → 2,4-Diethyl-4-methyl-1,5-diazaspiro[5.5]undec-1-ene

Reaction equation

[Br-:18].[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][OH:28].[K+:25].[K+:26].[NH2:1][C:2]([CH2:3][C:4]([CH2:5][CH3:6])=[O:7])([CH2:8][CH3:9])[CH3:10].[NH3:20].[NH4+:19].[O:11]=[C:12]1[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]1>>[NH:1]1[C:2]([CH2:8][CH3:9])([CH3:10])[CH2:3][C:4]([CH2:5][CH3:6])=[N:19][C:12]12[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2

Participants

Reactant 8

HCID 222Ammonia

HCID 223Ammonium

HCID 259Bromide ion

HCID 813Potassium Cation2×

HCID 887Methanol

HCID 7967Cyclohexanone

HCID 19660Carbonate Ion

HCID 213304575-Amino-5-methylheptan-3-one

Product 1

HCID 213304542,4-Diethyl-4-methyl-1,5-diazaspiro[5.5]undec-1-ene

Sources & evidence

ORD record: ord-4ec2bcb68f8b4c848198ccc9fbb728c8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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