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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 892129Generated: October 26, 2026

Ketamine → Esmolol

https://huagongshe.com/reaction/892129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantKetamineHCID 3821—
ReactantMetoprololHCID 4171—
ReactantPropranololHCID 4946—
ReactantXylazineHCID 5707—
ReactantAcepromazine MaleateHCID 6420038—
ReactantGs-9667HCID 11561692—
SolventDimethyl SulfoxideHCID 679—
ProductEsmololHCID 59768—

Reaction Steps

Rats (Sprague Dawley) weighing 300–400 gms were purchased from Simonsen laboratories. CVT-3619 was dissolved in DMSO and further diluted in saline. CVT-510 was dissolved in saline. Ketamine was purchased from Fort Dodge Animal Health, Xylazine from Bayer and Acepromazine Maleate from Fermenta Animal Health Co. Metoprolol and propranolol were purchased from SIGMA. Esmolol was obtained from a local pharmacy.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07005425B2
Source datasetuspto-grants-2006_02
ORD IDord-bcac1318381347d2948e2ade63e7ca79
Source noteuspto-grants-2006_02