1-(4-Bromophenyl)ethanol → 8-(2-Chloro-benzenesulfonyl)-2-[4-(1-hydroxy-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([CH:29]([CH3:30])[OH:31])[cH:27][cH:28]1.[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][NH:17][C:18]3=[O:19])[CH2:20][CH2:21]2)[cH:4][cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:23]4[cH:24][cH:25][c:26]([CH:29]([CH3:30])[OH:31])[cH:27][cH:28]4)[C:18]3=[O:19])[CH2:20][CH2:21]2)[cH:4][cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-50c7c3960fac46ecb6625db04fd40294
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…