Chloro(phenyl)acetyl chloride → HCID 19892257, compound

Reaction equation

[CH2:1]([O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:10])=[S:9])=[CH:6][CH:5]=1)[CH3:2].Cl[CH:14]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:15](Cl)=[O:16]>>[CH2:1]([O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]2[S:9][C:14]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[C:15]([OH:16])[N:10]=2)=[CH:6][CH:5]=1)[CH3:2]

Participants

Reactant 2

HCID 102902Chloro(phenyl)acetyl chloride

HCID 24431794-Ethoxybenzene-1-carbothioamide

Product 1

HCID 19892257HCID 19892257, compound

Procedure

The title compound was prepared according to the method of Scheme II in a manner analogous to Example 31 except 4-ethoxythiobenzamide was used instead of thiobenzamide and 2-chloro-2-phenylacetyl chloride was used instead of 2-bromopropionate.

Sources & evidence

ORD record: ord-fb72e8bc96c740b6aa7ab86ec4d04a13
Source dataset: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05124342

Reaction notes

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