4,5,6-Pyrimidinetriamine → 8-beta-D-ribofuranosyl adenine

HRID 894104

Reaction equation

HRID 894104 reaction equation
O=[C:2](O)[C@@H:3]1[O:9][C@H:8]([CH2:10][OH:11])[C@@H:6]([OH:7])[C@H:4]1[OH:5].[NH2:13][C:14]1[C:19]([NH2:20])=[C:18]([NH2:21])[N:17]=[CH:16][N:15]=1>>[C@@H:3]1([C:2]2[NH:20][C:19]3[C:14](=[N:15][CH:16]=[N:17][C:18]=3[NH2:21])[N:13]=2)[O:9][C@H:8]([CH2:10][OH:11])[C@@H:6]([OH:7])[C@H:4]1[OH:5]

Participants

3

Reactant 2

HCID 670494,5,6-PyrimidinetriamineHCID 574380752,5-Anhydroallonic acid

Product 1

HCID 218294858-beta-D-ribofuranosyl adenine

Procedure

Hydrolysis of this product yielded 2,5-anhydroallonic acid and reaction of this acid with 4,5,6-triamino pyrimidine, after cyclization, yielded the nucleoside, 8-β-D-ribofuranosyl adenine.

Workup

  1. customHydrolysis of this product
  2. customyielded

Sources & evidence

ORD record
ord-9396dd7f8c5a4a00ac9b873beb5fb3b6
Source dataset
uspto-grants-1981_08
Patent number
US04282349

Linked notes

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