1-methyl-3-methylene-2-pyrrolidinone → HCID 20574747, compound

Reaction equation

[CH3:1][N:2]1[CH2:6][CH2:5][C:4](=[CH2:7])[C:3]1=[O:8].C=C1CCCNC1=[O:16]>>[CH2:7]=[C:4]([CH2:5][CH2:6][NH:2][CH3:1])[C:3]([OH:8])=[O:16]

Participants

Reactant 2

HCID 108443541-methyl-3-methylene-2-pyrrolidinone

HCID 111825893-Methylidene-2-piperidinone

Product 1

HCID 20574747HCID 20574747, compound

Procedure

By substituting 1-methyl-3-methylene-2-pyrrolidinone [J. Org. Chem., 39, 893 (1974)] for the 3-methylene-2-piperidone in the procedure of Example 9, 2-methylene-4-methylaminobutanoic acid hydrochloric is obtained.

Sources & evidence

ORD record: ord-366b062a3a0844f9969b7ae744624e44
Source dataset: uspto-grants-1981_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04284779

Reaction notes

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