Cyclododecanone → 1-(Dimethylamino-propoxyimino)cyclododecane

Reaction equation

[C:1]1(=O)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.Cl.[CH3:16][N:17]([CH2:19][CH2:20][CH2:21][O:22][NH2:23])[CH3:18].C(O)(=O)/C=C/C([O-])=O>>[CH3:16][N:17]([CH2:19][CH2:20][CH2:21][O:22][N:23]=[C:1]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[CH3:18]

Participants

Reactant 3

HCID 13246Cyclododecanone

HCID 6183479Fumarate(1-)

HCID 21884286O-(3-(dimethylamino)propyl)hydroxylamine dihydrochloride

Product 1

HCID 132058011-(Dimethylamino-propoxyimino)cyclododecane

Procedure

Starting from 18.23 g. (0.1 moles) of cyclododecanone and 21.0 g. (0.11 moles) of dimethylaminopropoxyamine dihydrochloride the title compound is prepared as in Example 13. Yield: 20.9 g. (74%). Hydrogen fumarate, m.p.: 117°-118° C.

Sources & evidence

ORD record: ord-ffc81a4867ab4582a30f57af21e9fe3a
Source dataset: uspto-grants-1981_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04285942

Reaction notes

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