Iodine → 3,3'-Disulfanediylbis(n,n-dimethylpropan-1-amine)
Reaction equation
II.[CH3:3][N:4]([CH3:9])[CH2:5][CH2:6][CH2:7][SH:8].[OH-].[Na+]>CCOCC>[CH3:3][N:4]([CH3:9])[CH2:5][CH2:6][CH2:7][S:8][S:8][CH2:7][CH2:6][CH2:5][N:4]([CH3:9])[CH3:3]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Iodine is added portionwise to a mixture of 4 g of 3-dimethylaminopropylmercaptan in 60 ml of ether and 30 ml of 2-N sodium hydroxide solution until the solution is no longer decolorised each time (ca 4.2 g of iodine). After stirring for 1 hour, the ether phase is dried over magnesium sulphate, concentrated and fractionally distilled at 95°-100° C./0.025 mmHg. 2.7 g (68%) of 3-dimethylaminopropyl disulphide are obtained in the form of a clear colourless liquid.
Workup
- dry with materialthe ether phase is dried over magnesium sulphate
- concentrationconcentrated
- distillationfractionally distilled at 95°-100° C./0.025 mmHg
Sources & evidence
- ORD record
- ord-8d4c3d502ae24f3c85d597ccf02b3086
- Source dataset
- uspto-grants-1981_08
- Patent number
- US04285984
Reaction notes
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