Acetate → L-Pantothenic acid

HRID 895092Notes

Reaction equation

HRID 895092 reaction equation
[C:1]([O-:15])(=[O:14])[CH2:2][CH2:3][NH:4][C:5](=[O:13])[C@H:6]([C:8]([CH2:11][OH:12])([CH3:10])[CH3:9])[OH:7].C([O-])(=O)C>CO>[C:1]([OH:15])(=[O:14])[CH2:2][CH2:3][NH:4][C:5](=[O:13])[C@H:6]([C:8]([CH2:11][OH:12])([CH3:10])[CH3:9])[OH:7]

Participants

4

Reactant 2

HCID 175AcetateHCID 6997253d-Pantothenate

Product 1

HCID 5748353L-Pantothenic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The concentration of the D-pantothenate formed is then determined in the culture supernatant centrifuged off by means of High Performance Liquid Chromatography [column: Reversed Phase MZ-Aqua Perfect (diameter 4,6 mm), mobile Phase 25 mM acetate buffer with 10% methanol, flow rate 1 ml/min, RI detector].

Sources & evidence

ORD record
ord-68e575db07c546078c72747b29faad80
Source dataset
uspto-grants-2005_07
Patent number
US06913912B2

Reaction notes

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