3-Chloropyridin-4-amine → N-(3-chloropyridin-4-yl)-8-(difluoromethoxy)-2-(trifluoromethyl)quinoline-5-carboxamide
Reaction equation
[N+:1]([c:2]1[cH:3][cH:4][c:5]([O:10][C:11](=[O:6])[c:13]2[c:14]3[cH:15][cH:16][c:17]([C:27]([F:28])([F:29])[F:30])[n:18][c:19]3[c:20]([O:23][CH:24]([F:25])[F:26])[cH:21][cH:22]2)[cH:7][cH:8]1)([O-:9])=[O:12].[NH2:31][c:32]1[c:33]([Cl:38])[cH:34][n:35][cH:36][cH:37]1>>[O:10]=[C:11]([c:13]1[c:14]2[cH:15][cH:16][c:17]([C:27]([F:28])([F:29])[F:30])[n:18][c:19]2[c:20]([O:23][CH:24]([F:25])[F:26])[cH:21][cH:22]1)[NH:31][c:32]1[c:33]([Cl:38])[cH:34][n:35][cH:36][cH:37]1Participants
3
Sources & evidence
- ORD record
- ord-2bef97d569354f4481783e160625897a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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