2-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-one → 2-(3,4-Dimethoxyphenyl)-7-methoxyimidazo[1,2-a]pyridine

HRID 895455

Reaction equation

HRID 895455 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][N:3]=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[C:15](=O)[CH2:16]Br>>[CH3:10][O:11][C:12]1[CH:13]=[C:14]([C:15]2[N:1]=[C:2]3[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][N:3]3[CH:16]=2)[CH:19]=[CH:20][C:21]=1[O:22][CH3:23]

Participants

3

Reactant 2

HCID 2704232-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-oneHCID 108987152-Amino-4-Methoxypyridine

Product 1

HCID 98354982-(3,4-Dimethoxyphenyl)-7-methoxyimidazo[1,2-a]pyridine

Procedure

The title compound, pale yellow solid, m.p. 142° C. and MS: m/e=284.1 (M+), was prepared in accordance with the general method of example 1 from 2-amino-4-methoxy-pyridine and 3,4-dimethoxy-phenacylbromide.

Sources & evidence

ORD record
ord-8f3e79917a7e42a8a3fc4eb62e4e26ab
Source dataset
uspto-grants-2005_07
Patent number
US06916826B2

Linked notes

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