2-(2-Methyl-2-nitropropyl)naphthalene → alpha,alpha-Dimethyl-2-naphthaleneethanamine
Reaction equation
[CH3:1][C:2]([N+:15]([O-])=O)([CH3:14])[CH2:3][C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1>[Ni].C(O)C>[CH3:14][C:2]([NH2:15])([CH3:1])[CH2:3][C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
Raney nickel W2 (200 mg) was suspended in ethanol (10 ml), to the suspension was added 2-(2-methyl-2-nitropropyl)naphthalene (134 mg) obtained in Step 5, and hydrogenation was performed at a pressure of 3.5 atom for 12 hr.
Sources & evidence
- ORD record
- ord-850220ed51ca439d8c25e5a01a31a0ff
- Source dataset
- uspto-grants-2005_07
- Patent number
- US06916956B2
Reaction notes
Loading…