Acetic Acid → 2-(3-Bromo-2-methylphenyl)-5-fluoroisoindoline-1,3-dione

Reaction equation

[Br:1][c:2]1[c:3]([CH3:9])[c:4]([NH2:5])[cH:6][cH:7][cH:8]1.[CH3:22][C:23](=[O:24])[OH:25].[F:10][c:11]1[cH:12][c:13]2[c:17]([cH:18][cH:19]1)[C:16](=[O:20])[O:15][C:14]2=[O:21]>>[Br:1][c:2]1[c:3]([CH3:9])[c:4]([N:5]2[C:14](=[O:15])[c:13]3[cH:12][c:11]([F:10])[cH:19][cH:18][c:17]3[C:16]2=[O:20])[cH:6][cH:7][cH:8]1

Participants

Reactant 3

HCID 176Acetic Acid

HCID 675721,3-Isobenzofurandione, 5-fluoro-

HCID 1235383-Bromo-o-toluidine

Product 1

HCID 593750082-(3-Bromo-2-methylphenyl)-5-fluoroisoindoline-1,3-dione

Sources & evidence

ORD record: ord-442ae37df9c1416992820bfaf41bb3b1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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