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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8981Generated: October 26, 2026

Ethyl indole-2-carboxylate → 3-(Dimethylaminophenylmethyl)-1H-indole-2-carboxylic Acid Ethyl Ester

https://huagongshe.com/reaction/8981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl indole-2-carboxylateHCID 73125—
ReactantMethanaminium, N-methyl-N-(phenylmethylene)-, chlorideHCID 11073839—
Product3-(Dimethylaminophenylmethyl)-1H-indole-2-carboxylic Acid Ethyl EsterHCID 9880205—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 1H-indole-2-carboxylic acid ethyl ester and benzylidene-dimethyl-ammonium chloride. For characterization, an ESI-MS was recorded:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-72da6cfad289430d96716ceae4346d94
Source noteuspto-grants-2006_08