Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8982Generated: October 25, 2026

Indole-2-carboxylic acid → 3-(Dimethylaminophenylmethyl)-1H-indole-2-carboxylic Acid

https://huagongshe.com/reaction/8982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-2-carboxylic acidHCID 72899—
ReactantMethanaminium, N-methyl-N-(phenylmethylene)-, chlorideHCID 11073839—
Product3-(Dimethylaminophenylmethyl)-1H-indole-2-carboxylic AcidHCID 9814641—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 1H-indole-2-carboxylic acid and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-4c19ce5b2ab74400bfa9da1319b50e23
Source noteuspto-grants-2006_08