Butanoic acid, 2-ethyl-3-oxo-, ethyl ester → Methyl 2-ethyl-3-hydroxybutanoate

HRID 898510

Reaction equation

HRID 898510 reaction equation
[CH2:1]([CH:3]([C:8](=[O:10])[CH3:9])[C:4]([O:6][CH3:7])=[O:5])[CH3:2].C(C(C(=O)C)C(OCC)=O)C>>[CH2:1]([CH:3]([CH:8]([OH:10])[CH3:9])[C:4]([O:6][CH3:7])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 79065Butanoic acid, 2-ethyl-3-oxo-, ethyl esterHCID 103534Butanoic acid, 2-ethyl-3-oxo-, methyl ester

Product 1

HCID 14360117Methyl 2-ethyl-3-hydroxybutanoateYield 50%

Procedure

Methyl 2-ethyl-3-hydroxybutyrate was prepared following the procedure as described in step 2) of Preparation Example 4, except for that methyl 2-ethyl-3-oxo-butyrate was used to replace for ethyl 2-ethyl-3-oxo-butyrate. Yield 50%.

Workup

  1. customof Preparation Example 4

Sources & evidence

ORD record
ord-c0e3fada6aea4a48b99ff87bfd864693
Source dataset
uspto-grants-2008_04
Patent number
US07351778B2

Linked notes

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