3-Chloro-4-pyrrolidin-1-ylmethyl-phenylamine → N-(3-chloro-4-pyrrolidin-1-ylmethyl-phenyl)-2-(2-chloro-4-trifluoromethyl phenoxy)-acetamide
Reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([OH:8])=O.[Cl:17][C:18]1[CH:19]=[C:20]([NH2:30])[CH:21]=[CH:22][C:23]=1[CH2:24][N:25]1[CH2:29][CH2:28][CH2:27][CH2:26]1>>[Cl:17][C:18]1[CH:19]=[C:20]([NH:30][C:6](=[O:8])[CH2:5][O:4][C:3]2[CH:9]=[CH:10][C:11]([C:13]([F:16])([F:15])[F:14])=[CH:12][C:2]=2[Cl:1])[CH:21]=[CH:22][C:23]=1[CH2:24][N:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1Participants
3
Procedure
The product was prepared according to general working method I from (2-chloro-4-trifluoromethyl-phenoxy)-acetic acid (Z2b) and 3-chloro-4-pyrrolidin-1-ylmethyl-phenylamine (140b).
Workup
- customThe product was prepared