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N-(2-Dimethylaminoethyl)-N-methylbenzene-1,4-diamine → 2-(2-Chloro-4-trifluoromethyl-phenoxy)-n-{4-[(2-dimethylamino-ethyl)-methyl-amino]-phenyl}-acetamide

HRID 898590
Notes
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Reaction equation

HRID 898590 reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([OH:8])=O.[CH3:17][N:18]([CH3:30])[CH2:19][CH2:20][N:21]([CH3:29])[C:22]1[CH:27]=[CH:26][C:25]([NH2:28])=[CH:24][CH:23]=1>>[Cl:1][C:2]1[CH:12]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([NH:28][C:25]1[CH:24]=[CH:23][C:22]([N:21]([CH2:20][CH2:19][N:18]([CH3:30])[CH3:17])[CH3:29])=[CH:27][CH:26]=1)=[O:8]
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 21873395N-(2-Dimethylaminoethyl)-N-methylbenzene-1,4-diamineHCID 59691547(2-Chloro-4-trifluoromethyl-phenoxy)-acetic acid

Product 1

HCID 596917072-(2-Chloro-4-trifluoromethyl-phenoxy)-n-{4-[(2-dimethylamino-ethyl)-methyl-amino]-phenyl}-acetamide

Procedure

The product was prepared according to general working method I from (2-chloro-4-trifluoromethyl-phenoxy)-acetic acid (Z2b) and N-(2-dimethylamino-ethyl)-N-methylbenzene-1,4-diamine (141b).

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-fc52c2b255464fe697d69106bfd4de37
Source dataset
uspto-grants-2008_04
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US07351719B2

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes