1H-indol-4-ol → 3-(Dimethylaminophenylmethyl)-1H-indol-4-ol

HRID 8987

Reaction equation

HRID 8987 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl-].[CH:12](=[N+:19]([CH3:21])[CH3:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH3:20][N:19]([CH:12]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:4]1[C:3]2[C:2]([OH:1])=[CH:10][CH:9]=[CH:8][C:7]=2[NH:6][CH:5]=1)[CH3:21]

Participants

3

Reactant 2

HCID 754211H-indol-4-olHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

Product 1

HCID 98784763-(Dimethylaminophenylmethyl)-1H-indol-4-ol

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 4-hydroxy-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Workup

  1. customhad been prepared in accordance with example 1

Sources & evidence

ORD record
ord-0be84a70ba3545d5b8875c78bac9b1ac
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

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