2-Methyl-5-nitro-1H-indole → Dimethyl-[(2-methyl-5-nitro-1H-indol-3-yl)-phenylmethyl]-amine

HRID 8992

Reaction equation

HRID 8992 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([N+:11]([O-:13])=[O:12])=[CH:6][CH:5]=2.[Cl-].[CH:15](=[N+:22]([CH3:24])[CH3:23])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:23][N:22]([CH3:24])[CH:15]([C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:11]([O-:13])=[O:12])[CH:8]=2)[NH:3][C:2]=1[CH3:1])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 2803132-Methyl-5-nitro-1H-indoleHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

Product 1

HCID 9815134Dimethyl-[(2-methyl-5-nitro-1H-indol-3-yl)-phenylmethyl]-amine

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-5-nitro-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Workup

  1. customhad been prepared in accordance with example 1

Sources & evidence

ORD record
ord-ee61190596024eeb8d48adec2e37d056
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

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