1H-indole-6-carboxylic acid → 3-(Dimethylaminophenylmethyl)-1H-indole-6-carboxylic Acid

HRID 8995

Reaction equation

HRID 8995 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([OH:12])=[O:11])[CH:8]=2)[CH:3]=[CH:2]1.[Cl-].[CH:14](=[N+:21]([CH3:23])[CH3:22])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH3:22][N:21]([CH:14]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:3]1[C:4]2[C:9](=[CH:8][C:7]([C:10]([OH:12])=[O:11])=[CH:6][CH:5]=2)[NH:1][CH:2]=1)[CH3:23]

Participants

3

Reactant 2

HCID 5952301H-indole-6-carboxylic acidHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

Product 1

HCID 98791993-(Dimethylaminophenylmethyl)-1H-indole-6-carboxylic Acid

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 1H-indole-6-carboxylic acid and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Workup

  1. customhad been prepared in accordance with example 1

Sources & evidence

ORD record
ord-7201ea0d60174d3f87bb02bbc4e730d0
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

Loading…