1-ethyl-2-phenyl-1H-indole → 1-Ethyl-2-phenyl-3-(pyrrolidin-1-yl-o-tolylmethyl)-1H-indole

HRID 9002

Reaction equation

HRID 9002 reaction equation
[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2].[Cl-].[CH3:19][C:20]1[CH:31]=[CH:30][CH:29]=[CH:28][C:21]=1[CH:22]=[N+:23]1[CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH:22]([N:23]2[CH2:27][CH2:26][CH2:25][CH2:24]2)[C:21]2[CH:28]=[CH:29][CH:30]=[CH:31][C:20]=2[CH3:19])=[C:4]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2]

Participants

3

Reactant 2

HCID 832481-ethyl-2-phenyl-1H-indoleHCID 179122801-(2-Methyl-benzylidene)-pyrrolidinium chloride

Product 1

HCID 102940521-Ethyl-2-phenyl-3-(pyrrolidin-1-yl-o-tolylmethyl)-1H-indole

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 1-ethyl-2-phenyl-1H-indole and 1-(2-methyl-benzylidene)-pyrrolidinium chloride

Sources & evidence

ORD record
ord-51710e2fadba4c6ebef8fb7d62ebc731
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

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