1-ethyl-2-phenyl-1H-indole → 3-[(2-Chlorophenyl)-piperidin-1-yl-methyl]-1-ethyl-2-phenyl-1H-indole
Reaction equation
[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2].[Cl-].[Cl:19][C:20]1[CH:32]=[CH:31][CH:30]=[CH:29][C:21]=1[CH:22]=[N+:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[Cl:19][C:20]1[CH:32]=[CH:31][CH:30]=[CH:29][C:21]=1[CH:22]([N:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1)[C:5]1[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[N:3]([CH2:1][CH3:2])[C:4]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1Participants
3
Procedure
The preparation was carried out in accordance with general synthesis instructions 4 from 1-ethyl-2-phenyl-1H-indole and 1-(2-chloro-benzylidene)-piperidinium chloride
Sources & evidence
- ORD record
- ord-ff9a8d4fad55412297bdb1e95d7c1e2d
- Source dataset
- uspto-grants-2006_08