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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9015Generated: October 26, 2026

4-Methylindole → 4-Methyl-3-(piperidin-1-yl-o-tolylmethyl)-1H-indole

https://huagongshe.com/reaction/9015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylindoleHCID 85282—
Reactant1-(2-Methyl-benzylidene)-piperidinium chlorideHCID 17912257—
Product4-Methyl-3-(piperidin-1-yl-o-tolylmethyl)-1H-indoleHCID 9966775—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 4-methyl-1H-indole and 1-(2-methyl-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 30.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-196c1c862b4c4bf289afa7d0c7189a58
Source noteuspto-grants-2006_08