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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9024Generated: October 26, 2026

5-Chloroindole → 5-Chloro-3-[(2-methoxyphenyl)-piperidin-1-yl-methyl]-1H-indole

https://huagongshe.com/reaction/9024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-ChloroindoleHCID 87110—
Reactant1-(2-Methoxy-benzylidene)-piperidinium chlorideHCID 17912276—
Product5-Chloro-3-[(2-methoxyphenyl)-piperidin-1-yl-methyl]-1H-indoleHCID 10108836—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and 1-(2-methoxy-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 40.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-c2eb1b549dd94deb901c071c6cc58834
Source noteuspto-grants-2006_08