2-(4-Methoxyphenyl)propan-1-amine → 2-Phenyl-4-methylpentylamine

HRID 902748

Reaction equation

HRID 902748 reaction equation
[C:1]1([CH:7]([CH2:11][CH:12]([CH3:14])[CH3:13])[C:8]([NH2:10])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.COC1C=CC(C(C)CN)=CC=1>>[C:1]1([CH:7]([CH2:11][CH:12]([CH3:14])[CH3:13])[CH2:8][NH2:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 2026252-(4-Methoxyphenyl)propan-1-amineHCID 3162092-Phenyl-4-methylpentanoic acid amide

Product 1

HCID 207282122-Phenyl-4-methylpentylamineYield 51%

Procedure

The titled compound was prepared from 2-phenyl-4-methylpentanoic acid amide in 51% yield in the same manner as the preparation of 2-(4-methoxyphenyl)propylamine in Example 188c. MS (ESI) 178 (MH+)

Sources & evidence

ORD record
ord-0139beff46494013a3dd85703b0d2ab8
Source dataset
uspto-grants-2008_04
Patent number
US07365085B2

Linked notes

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