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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9030Generated: October 26, 2026

Dimethylamine → [(5-Bromo-2-fluoro-phenyl)-(4-nitro-1H-indol-3-yl)-methyl]-dimethyl-amine

https://huagongshe.com/reaction/9030

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant4-Nitro-1H-indoleHCID 145766—
Reactant5-Bromo-2-fluorobenzaldehydeHCID 736327—
Reactant(5-Bromo-2-fluoro-benzylidene)-dimethyl-ammonium chlorideHCID 21985366—
Product[(5-Bromo-2-fluoro-phenyl)-(4-nitro-1H-indol-3-yl)-methyl]-dimethyl-amineHCID 21985281—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 4-nitroindole and (5-bromo-2-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 5-bromo-2-fluoro-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-07c36c5d800843d9967723d5d67b4e5f
Source noteuspto-grants-2006_08