3-Amino-2-butenenitrile → 5-Amino-3-methyl-1-(4-chloro-2-methylphenyl) pyrazole

HRID 903073

Reaction equation

HRID 903073 reaction equation
[ClH:1].Cl[C:3]1[CH:4]=[CH:5][C:6]([CH3:11])=[C:7]([NH:9][NH2:10])[CH:8]=1.N[C:13]([CH3:17])=[CH:14][C:15]#[N:16]>>[NH2:16][C:15]1[N:9]([C:7]2[CH:8]=[CH:3][C:4]([Cl:1])=[CH:5][C:6]=2[CH3:11])[N:10]=[C:13]([CH3:17])[CH:14]=1

Participants

3

Reactant 2

HCID 706993-Amino-2-butenenitrileHCID 13200574(5-Chloro-2-methylphenyl)hydrazine hydrochloride

Product 1

HCID 127637865-Amino-3-methyl-1-(4-chloro-2-methylphenyl) pyrazole

Procedure

5-chloro-2-methylphenylhydrazine HCl (80.32 g.) was reacted with 3-amino-2-butene nitrile (32.5 g.) as described in Example XLIII to give 60.5 g. product, mp 86°-87°.

Workup

  1. customto give 60.5 g

Sources & evidence

ORD record
ord-676710e2a5df43ff9f9e2439791ed12a
Source dataset
uspto-grants-1980_10
Patent number
US04226773

Linked notes

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