HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → [(5-Bromo-2-fluoro-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 1-Methylindole | HCID 11781 | — |
| Reactant | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| Reactant | (5-Bromo-2-fluoro-benzylidene)-dimethyl-ammonium chloride | HCID 21985366 | — |
| Product | [(5-Bromo-2-fluoro-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine | HCID 21985304 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 1-methylindole and (5-bromo-2-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 5-bromo-2-fluoro-benzaldehyde and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091220B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-598639165ac04cc8a8c4efb2e52fbbdb |
| Source note | uspto-grants-2006_08 |