Phenol → 7-Chloro-10-[(5-diethylaminopentyl)amino]-2-methoxypyrido[3,2-b]quinoline dihydrochloride

HRID 903147

Reaction equation

HRID 903147 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](Cl)=[C:7]3[N:15]=[C:14]([O:16][CH3:17])[CH:13]=[CH:12][C:8]3=[N:9][C:10]=2[CH:11]=1.[CH2:19]([N:21]([CH2:28][CH3:29])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][NH2:27])[CH3:20].C1(O)C=CC=CC=1>>[ClH:1].[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]([NH:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][N:21]([CH2:28][CH3:29])[CH2:19][CH3:20])=[C:7]3[N:15]=[C:14]([O:16][CH3:17])[CH:13]=[CH:12][C:8]3=[N:9][C:10]=2[CH:11]=1

Participants

4

Reactant 3

HCID 996PhenolHCID 231071-Aza-6,9-dichloro-2-methoxyacridineHCID 4584949(5-Aminopentyl)diethylamine

Product 1

HCID 233378127-Chloro-10-[(5-diethylaminopentyl)amino]-2-methoxypyrido[3,2-b]quinoline dihydrochloride

Procedure

A mixture of 2.8 g. of 7,10-dichloro-2-methoxypyrido [3,2-b]quinoline, 1.7 g. of 5-diethylaminopentylamine and 6.5 g. of phenol was treated as in Example 5 to obtain the title compound, m.p. 232°-233° C.

Workup

  1. additionA mixture of 2.8 g

Sources & evidence

ORD record
ord-247bbeead2774ae58674794bd14272da
Source dataset
uspto-grants-1980_10
Patent number
US04226869

Linked notes

Loading…