Iodine → HCID 53818980, compound
Reaction equation
II.[I-].[K+].[SH:5][C:6](=[CH:10][C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:7]([OH:9])=[O:8]>O.C(#N)C>[O:12]1[CH:13]=[CH:14][CH:15]=[C:11]1[CH:10]=[C:6]([S:5][S:5][C:6](=[CH:10][C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:7]([OH:9])=[O:8])[C:7]([OH:9])=[O:8]Participants
6
Reactant 3
Product 1
Reagents, catalysts & solvents 2
Procedure
Iodine is added to a solution of 100 g of potassium iodide in 500 ml of water to saturation. This saturated solution is added dropwise to a solution of α-mercapto-β-(2-furyl)acrylic acid in 500 ml of acetonitrile and 30 ml of water until the color of iodine persists. The crude product which precipitates is recrystallized from methanol. M.P. 215° C.
Workup
- customThe crude product which precipitates
- customis recrystallized from methanol
Sources & evidence
- ORD record
- ord-6c7f75c37b49474c83e1e00364b63175
- Source dataset
- uspto-grants-1980_10
- Patent number
- US04226882
Reaction notes
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