Ethyl 3-(6-methylpyridin-3-yl)prop-2-enoate → Ethyl 3-(6-methyl-3-pyridyl)propionate
Reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1>C(O)C.[Pd]>[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
Ethyl 3-(6-methyl-3-pyridyl)acrylate (60.36 g) was hydrogenated in ethanol at 35° and 355 kPa using palladiumon charcoal catalyst (10%, 1.0 g). The mixture was filtered and the filtrate was evaporated to give ethyl 3-(6-methyl-3-pyridyl)propionate as an oil.
Workup
- filtrationThe mixture was filtered
- customthe filtrate was evaporated
Sources & evidence
- ORD record
- ord-15181f4a07c3428ebdc72c873a73d5dc
- Source dataset
- uspto-grants-1980_10
- Patent number
- US04227000
Reaction notes
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