Dimethylamine → [(2-Chloro-6-fluoro-phenyl)-(4-nitro-1H-indol-3-yl)-methyl]-dimethyl-amine
Reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH:6]=[CH:7][NH:8]2)([O-:3])=[O:2].[Cl-].[Cl:14][C:15]1[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:16]=1[CH:17]=[N+:18]([CH3:20])[CH3:19].ClC1C=CC=C(F)C=1C=O.CNC>>[Cl:14][C:15]1[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:16]=1[CH:17]([N:18]([CH3:20])[CH3:19])[C:6]1[C:5]2[C:9](=[CH:10][CH:11]=[CH:12][C:4]=2[N+:1]([O-:3])=[O:2])[NH:8][CH:7]=1Participants
5
Procedure
The preparation was carried out in accordance with general synthesis instructions 4 from 4-nitroindole and (2-chloro-6-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2-chloro-6-fluoro-benzaldehyde and dimethylamine.