Ethyl 2-Formylpropionate → HCID 23334400, compound

HRID 903787

Reaction equation

HRID 903787 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[CH2:5][NH:6][NH2:7].C([O:14][C:15](=O)[CH:16]([CH:18]=O)[CH3:17])C>C(O)C>[CH3:18][C:16]1[C:15](=[O:14])[N:6]([CH2:5][C:4]2[CH:8]=[CH:9][C:10]([Cl:11])=[C:2]([Cl:1])[CH:3]=2)[NH:7][CH:17]=1

Participants

4

Reactant 2

HCID 10898741Ethyl 2-FormylpropionateHCID 20495842HCID 20495842, compound

Product 1

HCID 23334400HCID 23334400, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10.9 g of 3,4-dichlorobenzylhydrazine were added dropwise to a solution of 7.5 g of α-formylpropionic acid ethyl ester in 50 ml of ethanol. After stirring overnight at room temperature, the solvent was distilled off in vacuo and the solid residue was recrystallized from ethanol.

Workup

  1. distillationthe solvent was distilled off in vacuo
  2. customthe solid residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-508d41bc7d304441a576d4d49e93ca88
Source dataset
uspto-grants-1980_10
Patent number
USRE030420

Linked notes

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