Peracetic Acid → HCID 19010447, compound
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[O:5][C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1.C(OO)(=[O:17])C>C(O)(=O)C>[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[O:5][C:6]1[CH:7]=[N+:8]([O-:17])[CH:9]=[CH:10][CH:11]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 32 g of 3-(3-fluorophenoxy)pyridine [Fr. Pat. No. 1,472,619 (1967)] in 50 ml of glacial acetic acid is treated with 35 g of 40% peracetic acid in acetic acid and the mixture is refluxed 16 hours. The mixture is concentrated at reduced pressure and the oil is dissolved in 250 ml of dichloromethane. The dichloromethane solution is washed with excess 10% sodium hydroxide solution. The solution is dried and concentrated to dryness to yield 3-(3-fluorophenoxy)pyridine 1-oxide, m.p. 63°-66° C.