9-(2-cyclohexenyl)-2-propoxy-9H-adenine → 9-Cyclohexyl-2-n-propoxy-9H-adenine
Reaction equation
[CH:1]1([N:7]2[CH:15]=[N:14][C:13]3[C:8]2=[N:9][C:10]([O:17][CH2:18][CH2:19][CH3:20])=[N:11][C:12]=3[NH2:16])[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1>C(O)C.[Pd]>[CH:1]1([N:7]2[CH:15]=[N:14][C:13]3[C:8]2=[N:9][C:10]([O:17][CH2:18][CH2:19][CH3:20])=[N:11][C:12]=3[NH2:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A solution of 2.21 g (7.8 mmoles) of 9-(2-cyclohexenyl)-2-propoxy-9H-adenine in 30 mL of 90% ethanol was hydrogenated overnight with 250 mg of 10% palladium on carbon and then filtered. The filtrate was evaporated in vacuo, giving a residue which was crystallized from ethyl acetate--n-hexane. Yield 1.85 g (76%); melting point 148°-150° C.