HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → [(2-Chloro-4-fluoro-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 2-Methylindole | HCID 7224 | — |
| Reactant | 2-Chloro-4-fluorobenzaldehyde | HCID 145024 | — |
| Reactant | (2-Chloro-4-fluoro-benzylidene)-dimethylammonium chloride | HCID 21985315 | — |
| Product | [(2-Chloro-4-fluoro-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine | HCID 21985360 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (2-chloro-4-fluoro-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-chloro-4-fluoro-benzaldehyde and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091220B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-f9cc66bc533c45fc829f8836d582b65f |
| Source note | uspto-grants-2006_08 |