HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → [[2-(3-Chloro-4-fluoro-phenyl)-1H-indol-3-yl]-(3,4-dimethoxy-phenyl)-methyl]-dimethyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Veratraldehyde | HCID 8419 | — |
| Reactant | 2-(3-Chloro-4-fluorophenyl)indole | HCID 2736577 | — |
| Reactant | (3,4-Dimethoxy-benzylidene)-dimethylammonium chloride | HCID 21985355 | — |
| Product | [[2-(3-Chloro-4-fluoro-phenyl)-1H-indol-3-yl]-(3,4-dimethoxy-phenyl)-methyl]-dimethyl-amine | HCID 69377412 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 2-(3-chloro-4-fluoro-phenyl)-1H-indole and (3,4-dimethoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 3,4-dimethoxy-benzaldehyde and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091220B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-8fb4a0784c5e46a29b0b5a6f2dcabd3f |
| Source note | uspto-grants-2006_08 |