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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9064Generated: October 25, 2026

Dimethylamine → [(4-Fluoro-phenyl)-(4-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

https://huagongshe.com/reaction/9064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant4-MethylindoleHCID 85282—
Reactant(4-Fluoro-benzylidene)-dimethylammonium chlorideHCID 21985328—
Product[(4-Fluoro-phenyl)-(4-methyl-1H-indol-3-yl)-methyl]-dimethyl-amineHCID 21985345—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 4-methyl-1H-indole and (4-fluoro-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 4-fluoro-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-e8415c5d0b5f45968db469e1e4e5f5f1
Source noteuspto-grants-2006_08