3-(2-Benzyloxy-ethylamino)-phthalic acid dimethyl ester → 3-(2-Benzyloxy-ethylamino)-phthalic acid

HRID 906746

Reaction equation

HRID 906746 reaction equation
C[O:2][C:3](=[O:25])[C:4]1[C:5](=[C:10]([NH:14][CH2:15][CH2:16][O:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:11]=[CH:12][CH:13]=1)[C:6]([O:8]C)=[O:7].COCCNC1C=CC=C(C(O)=O)C=1C(O)=O>>[CH2:18]([O:17][CH2:16][CH2:15][NH:14][C:10]1[CH:11]=[CH:12][CH:13]=[C:4]([C:3]([OH:25])=[O:2])[C:5]=1[C:6]([OH:8])=[O:7])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 210401393-(2-Benzyloxy-ethylamino)-phthalic acid dimethyl esterHCID 219885193-(2-Methoxy-ethylamino)-phthalic acid

Product 1

HCID 219885823-(2-Benzyloxy-ethylamino)-phthalic acid

Procedure

3-(2-Benzyloxy-ethylamino)-phthalic acid dimethyl ester (2.50 g, 7.28 mmol) was treated in the same manner as described above for the synthesis of 3-(2-methoxy-ethylamino)-phthalic acid. The product of the reaction, which contained a mixture of diacid and monomethyl esters, was used without further purification.

Workup

  1. customThe product of the reaction, which
  2. customwas used without further purification

Sources & evidence

ORD record
ord-6603772c113d485b808c5e1aacd4e3d2
Source dataset
uspto-grants-2011_09
Patent number
US08012997B2

Linked notes

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